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Four kinds of people end up here. See which one you are.
Cravings + crashes
Afternoon crashes, snack urgency, and the feeling that appetite always gets the last word.
CLADE is positioned as a more complete metabolic-support system, not a one-ingredient shortcut.
More than berberine
You got partial results from berberine but still felt like the category stopped too early.
Stacking multiple mechanisms gives you a stronger "why this instead" answer than single-ingredient formulas.
Metabolic resistance
Numbers that drift, energy that feels inconsistent, or the sense that your metabolism is not working with you.
CLADE is built to support metabolism from more than one angle instead of making one claim do everything.
Label readers
You compare ingredients, read doses, and do not trust vague wellness marketing.
Transparent dosing and patented actives make this easy to verify for yourself.
Metabolic support compounds when the routine is consistent long enough to show up in real life.
Akkermansia colonization begins. Many notice reduced bloating and fewer post-meal sugar cravings. Gut comfort improves as the prebiotic system activates.
The afternoon crash diminishes. Portion control becomes easier without willpower. Blood sugar swings feel less dramatic. You stop reaching for snacks between meals.
Daily energy steadies and cravings ease for many users. Body composition changes become noticeable. The gut-GLP-1 axis is functioning at full capacity.
Full benefits of consistent supplementation. Stable blood sugar, predictable energy, reduced cravings, and maintained metabolic markers. This is the new baseline.
What Makes This Different
Most GLP-1 supplements are just repackaged berberine at unclear doses. CLADETM pairs 410mg of patented Sugaheal® with a small 20mg supporting dose of Dihydro Berberine: a more bioavailable form of berberine. Sugaheal is clinically studied for healthy glucose metabolism. Sugaheal supports glucose metabolism through a separate metabolic pathway, without the GI issues associated with high-dose standalone berberine. Two ingredients working together, both doses printed on the label.
The Gut-GLP-1 Axis
Akkermansia muciniphila is a keystone gut bacterium clinically studied for its role in GLP-1 signaling and metabolic health. But Akkermansia needs fuel to colonize. Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut, with Beta Glucan providing additional prebiotic support. Standardized Vinomerix Optima® (16% Monomers & 80% OPCs from grape seed) completes the environment Akkermansia requires to thrive. No other supplement combines all of these in one capsule.
Full Formula Disclosure
Most metabolic supplements hide behind "GLP-1 Support Blend 800mg" with no breakdown. You have no idea how much Akkermansia or how little berberine you're actually getting. CLADETM prints every dose on the bottle. One patented extract (Sugaheal®) alongside standardized Vinomerix Optima®. Six clinically studied ingredients. 1,150mg of active compounds per serving. Zero guesswork.
Patricia W.
Steadier energy
"Steadier energy, fewer crashes"
I tried berberine for six months with barely any change. Two months on CLADETM, my afternoon energy stopped crashing and the constant snack cravings finally eased off. When I compared the label to the research, the Sugaheal dose lined up. Staying on this.
Karen S.
Label reader
"The only GLP-1 supplement I trust"
I read labels obsessively and I'm skeptical of every GLP-1 supplement out there. Most are berberine with a new label. CLADETM lists Akkermansia and Vinomerix at specific doses I can verify against published research. That's why it's the one I stuck with.
Danielle R.
Cravings relief
"The cravings went quiet"
By week three, I stopped reaching for something sweet after every meal. By month two, the afternoon energy crash was gone. I've tried berberine, chromium, apple cider vinegar supplements. This is the first time something actually shifted how my body handles sugar after meals.
Michael T.
Age 55
"Energy that holds through the afternoon"
I wanted something I could actually understand, every dose printed, nothing hidden in a blend. After three months of consistent use, my afternoon energy holds and the between-meal snacking has dropped off. The transparency is what won me over.
Christine B.
Age 47
"Cravings faded, energy came back"
It took about four weeks to really feel it. But once my digestion normalized and the sugar cravings faded, I was sold. Five months in now and steady afternoon energy is just my normal. I notice immediately when I skip a day.
Jennifer A.
Age 42
"Berberine alone wasn't enough"
I was taking 1000mg of generic berberine daily and still dealing with afternoon crashes and constant cravings. Switching to CLADETM, the combination of Sugaheal with the Akkermansia gut support made a noticeable difference within a month. The multi-pathway approach just made more sense to me.
Each ingredient dosed at the level where published research showed results. Not underdosed to cut costs. Not overdosed to pad a label.
Six ingredients selected for what they do individually and how they work together.
A patented botanical extract clinically studied for healthy glucose metabolism. Unlike commodity berberine with variable potency, Sugaheal is standardized and dosed at the level used in published clinical research. Sugaheal supports glucose metabolism through a separate metabolic pathway, without the GI issues associated with high-dose standalone berberine. Paired with a small 40mg supporting dose of Dihydro Berberine for complementary metabolic pathway coverage.
A more bioavailable form of berberine. At a small 20mg supporting dose, it complements Sugaheal through a separate metabolic pathway: avoiding the GI discomfort associated with high-dose standalone berberine.
A keystone gut bacterium that represents 1-5% of healthy gut flora. Clinically studied for its role in GLP-1 signaling, gut barrier integrity, and metabolic regulation. Akkermansia communicates directly with L-cells in the gut lining to support natural GLP-1 production.
Rich in inulin, a prebiotic fiber that specifically feeds Akkermansia muciniphila. Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut. Works with Beta Glucan as part of the prebiotic fuel system.
Standardized Grape Seed Extract (16% Monomers and 80% oligomeric proanthocyanidins / OPCs). Published research (PMC9834079) demonstrates that grape seed polyphenols promote Akkermansia growth in the gut microbiome, creating a synergistic effect with direct Akkermansia supplementation.
A soluble fiber with dual function: immune support and gut health. Beta Glucan supports healthy blood sugar levels by slowing glucose absorption and, alongside Chicory, helps feed Akkermansia and maintain a healthy gut environment. At 300mg, it provides effective fiber support without the digestive discomfort of higher doses.
FULL LABEL DISCLOSURE
Compare our label against the published research yourself. No proprietary blends, no fairy dust.
| Ingredient | Dose per Serving | Why This Dose |
|---|---|---|
| Sugaheal® | 410 mg | Patented extract dosed at the clinical research level, supporting glucose metabolism through its own distinct pathway. |
| Dihydro Berberine | 20 mg | A more bioavailable form of berberine, at a small supporting dose that complements Sugaheal’s separate metabolic pathway without the GI discomfort of high-dose standalone berberine. |
| Akkermansia muciniphila | 20 mg | Keystone gut bacterium that supports gut lining integrity and communicates with L-cells to support natural GLP-1 production. |
| Chicory Powder / Inulin | 200 mg | Prebiotic fiber that acts as a feeding substrate so Akkermansia can establish and maintain healthy populations in the gut. |
| Vinomerix Optima® | 200 mg | Standardized grape seed extract (16% monomers, 80% OPCs) that supports beneficial gut bacteria growth alongside antioxidant defense. |
| Beta Glucan | 300 mg | Soluble fiber that feeds beneficial gut bacteria alongside Chicory and supports a healthy gut environment. |
| Excipients (capsule, anti-caking) | 200 mg | Standard capsule fill. |
2 capsules daily · 60 capsules · 30-day supply
Metabolic changes take time. If you don't notice improvements in 90 days, we'll refund you in full. No complicated forms, no judgment.
Subscribe and save. Every delivery ships free within the US. You save more and never have to think about reordering.
We want you to feel the results. If you're not happy, we'll give you a hassle-free, no-questions-asked refund processed immediately.
THE PROTOCOL 90 MEMBERSHIP
The 90-day plan is a full CLADE membership tier, not just a lower price.
Your full 90-day supply ships in a single shipment, so you’re never waiting on a reorder.
The 90-day plan is priced at $39/mo, CLADE’s lowest rate across every tier.
Manage your plan from your account any time up to 48 hours before your next renewal date.
Every quarterly order carries the full 90-day money-back guarantee, not just your first one.
Independent lab verification for purity, potency, and accurate dosage
Screened for lead, mercury, arsenic, and cadmium below FDA thresholds
Manufactured in a GMP-compliant facility
Every ingredient and its exact dose printed on the label
GLP-1 (glucagon-like peptide-1) is a hormone your body produces naturally in the gut. It regulates blood sugar, appetite, and metabolic health. CLADETM supports natural GLP-1 production through three pathways: Sugaheal + Dihydro Berberine for glucose metabolism, Akkermansia for gut-based GLP-1 signaling, and prebiotics (Chicory + Beta Glucan) to maintain the environment where GLP-1-producing cells thrive.
Sugaheal is a patented, standardized botanical extract: not generic berberine powder. It's dosed at 410mg based on clinical research for healthy glucose metabolism, and supports glucose metabolism through a separate metabolic pathway without the GI issues associated with high-dose standalone berberine. CLADETM also includes 40mg of Dihydro Berberine (a more bioavailable form of berberine) as a small supporting dose to cover a complementary glucose metabolism pathway. Different mechanisms, both at disclosed doses.
Akkermansia muciniphila communicates with L-cells in your gut to support GLP-1 production, but it needs the right environment to colonize. Standardized Vinomerix Optima® (grape seed OPCs) promotes Akkermansia growth (PMC9834079). Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut, with Beta Glucan providing additional prebiotic support. Together: the bacteria, the fuel, and the growth promoter.
Most people report reduced cravings and digestive improvements within 2-3 weeks. Energy stabilization follows by weeks 3-4. Metabolic markers like fasting glucose often improve at 6-8 weeks. Our 90-day guarantee covers the full adaptation period.
CLADETM is a dietary supplement, not a medication and not a replacement for prescription medication. If you take a prescription that affects blood sugar, talk to your doctor before starting so they can monitor your levels.
No. CLADETM is not a drug and not a replacement for prescription GLP-1 medication. Prescription GLP-1 drugs directly mimic the GLP-1 hormone. CLADETM instead supports your body's own natural GLP-1 production through nutritional and microbiome pathways. Talk to your healthcare provider if you're considering or currently on any prescription GLP-1 medication.
Take 2 capsules daily with your largest meal. Taking with food supports absorption and aligns with the natural post-meal metabolic window. Consistency matters more than exact timing.
Side effects are uncommon. Some people notice mild digestive adjustment during the first week as the gut microbiome shifts. Taking with food usually prevents this. If needed, start with one capsule daily for the first week.
Yes. Plant-based capsules. Free from gluten, dairy, soy, and GMOs. No artificial additives, fillers, or magnesium stearate.
90-day satisfaction guarantee on quarterly plans. 30-day guarantee on monthly plans. If you're not satisfied for any reason, contact us for a full refund. No complicated forms, no restocking fees. We cover return shipping.
Complete Your Protocol
Fiber feeds the same metabolic pathway this formula supports. Most members run both.
from $35/mo
View Formula →Or get both together as The Metabolic Protocol and save.
Transparent doses. Patented Sugaheal®. Multi-pathway metabolic support. Start with the quarterly plan for the strongest value and the full 90-day risk-free window.
The 90-Day GLP-1 Support Protocol is backed by a full 90-day risk-free guarantee. If you complete the protocol and your post-meal glucose curve, appetite signaling, or metabolic flexibility haven't shifted in ways you can feel, contact the team within 90 days for a full refund: no return required. The day-30 and day-60 milestones give you clear checkpoints so you know whether the protocol is working before the window closes.
You will receive an email notification before every charge. To pause or cancel, log into your customer account portal and manage your subscription in one click: no calls, no forms, no waiting period.
Log into your account portal and select "Skip next order." Your subscription resumes automatically on the following cycle. No charge is processed for the skipped month, and your pricing is preserved when you return.
