The 90-day protocol that supports your GLP-1 pathway, helps flatten post-meal glucose curves, and promotes steady appetite signaling: from day 30 through metabolic flexibility at day 90.
Patented Sugaheal® 410mg + Dihydro Berberine 40mg
Akkermansia + Vinomerix feed your gut's GLP-1 cells
6 ingredients targeting 3 metabolic pathways
Every dose printed on the label. Full formula disclosure.
Replaces 3+ supplements. Just $1.30/day (quarterly)
Choose your plan
The full arc: from first glucose response to lasting metabolic rhythm.
Billed $117.00 USD every 12 weeks
$1.30 / DAY
Billed $49.00 USD every 4 weeks
$1.63 / DAY
One-time. No subscription.
$1.97 / DAY
No commitment. Pause or cancel anytime: one click in your account.
Use the protocol daily for 90 days. If your post-meal glucose curve, appetite signaling, or metabolic flexibility haven't shifted, contact us for a full refund. Even on a finished bottle. No hoops, no usage questions, no return required. Applies to every plan.
Every batch of CLADE™ GLP-1 Metabolic Support is independently tested by a third-party laboratory for purity, potency, and heavy metals (lead, mercury, arsenic, cadmium). Certificates of analysis are available upon request. We test what we claim because transparency isn't optional.
Dosage: Take 2 capsules daily with a meal.
Why only 2 capsules? Our formula concentrates six active ingredients into just two capsules. Simple protocol, no complexity.
Tip: Take at the same time each day, ideally with your largest meal, for best absorption.
Supply: Each bottle contains 60 capsules (30-day supply).
Supplement Facts
Serving Size: 2 Capsules | Servings Per Container: 30
Total formula: 1,200mg per serving. Other ingredients: plant-based capsule (hypromellose), rice flour. No artificial additives, fillers, gluten, dairy, soy, or GMOs.
The page should quickly tell a reader whether this is for cravings, blood-sugar rhythm, metabolic resistance, or skepticism about the usual GLP-1 support category.
Cravings + crashes
Afternoon crashes, snack urgency, and the feeling that appetite always gets the last word.
CLADE is positioned as a more complete metabolic-support system, not a one-ingredient shortcut.
More than berberine
You got partial results from berberine but still felt like the category stopped too early.
The formula gives the page a stronger “why this instead” answer by stacking multiple mechanisms.
Metabolic resistance
Numbers that drift, energy that feels inconsistent, or the sense that your metabolism is not working with you.
CLADE is built to support metabolism from more than one angle instead of making one claim do everything.
Label readers
You compare ingredients, read doses, and do not trust vague wellness marketing.
Transparent dosing and patented actives make the page easier to believe fast.
Metabolic support compounds when the routine is consistent long enough to show up in real life.
Akkermansia colonization begins. Many notice reduced bloating and fewer post-meal sugar cravings. Gut comfort improves as the prebiotic system activates.
The afternoon crash diminishes. Portion control becomes easier without willpower. Blood sugar swings feel less dramatic. You stop reaching for snacks between meals.
Fasting glucose and A1C trends improve for many users. Body composition changes become noticeable. The gut-GLP-1 axis is functioning at full capacity.
Full benefits of consistent supplementation. Stable blood sugar, predictable energy, reduced cravings, and maintained metabolic markers. This is the new baseline.
What Makes This Different
Most GLP-1 supplements are just repackaged berberine at unclear doses. CLADETM pairs 410mg of patented Sugaheal® with a small 40mg supporting dose of Dihydro Berberine: a more bioavailable form of berberine. Sugaheal is clinically studied for HbA1c reduction. Sugaheal supports glucose metabolism through a separate metabolic pathway, without the GI issues associated with high-dose standalone berberine. Two ingredients working together, both doses printed on the label.
The Gut-GLP-1 Axis
Akkermansia muciniphila is a keystone gut bacterium clinically studied for its role in GLP-1 signaling and metabolic health. But Akkermansia needs fuel to colonize. Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut, with Beta Glucan providing additional prebiotic support. Standardized Vinomerix Optima® (16% Monomers & 80% OPCs from grape seed) completes the environment Akkermansia requires to thrive. No other supplement combines all of these in one capsule.
Full Formula Disclosure
Most metabolic supplements hide behind "GLP-1 Support Blend 800mg" with no breakdown. You have no idea how much Akkermansia or how little berberine you're actually getting. CLADETM prints every dose on the bottle. One patented extract (Sugaheal®) alongside standardized Vinomerix Optima®. Six clinically studied ingredients. 1,200mg of active compounds per serving. Zero guesswork.
Patricia W.
A1C support
"A full point drop in A1C"
I tried berberine for six months with barely any change. Two months on CLADETM, my endocrinologist noticed my A1C dropped a full point. She asked what changed. When I showed her the label, she said the Sugaheal dose lined up with clinical research she'd reviewed. Staying on this.
Karen S.
Provider-trusted
"The only GLP-1 supplement I trust"
As a nurse practitioner, I'm skeptical of every GLP-1 supplement out there. Most are berberine with a new label. CLADETM lists Akkermansia and Vinomerix at specific doses I can verify against published research. That's why I recommend it when patients ask about metabolic support.
Danielle R.
Cravings relief
"The cravings went quiet"
By week three, I stopped reaching for something sweet after every meal. By month two, the afternoon energy crash was gone. I've tried berberine, chromium, apple cider vinegar supplements. This is the first time something actually shifted how my body handles sugar after meals.
Michael T.
Age 55
"My doctor is talking about reducing metformin"
I was on metformin and looking for something to complement it. My doctor approved CLADETM because he could see exactly what was in it and at what dose. After three months of consistent use, we're discussing reducing my metformin. The lab numbers speak for themselves.
Christine B.
Age 47
"Fasting glucose in range for the first time in years"
It took about four weeks to really feel it. But once my digestion normalized and the sugar cravings faded, I was sold. Five months in now and my fasting glucose has been consistently in range for the first time in three years. I notice immediately when I skip a day.
Jennifer A.
Age 42
"Berberine alone wasn't enough"
I was taking 1000mg of generic berberine daily and still dealing with post-meal spikes and afternoon crashes. Switching to CLADETM, the combination of Sugaheal with the Akkermansia gut support made a noticeable difference within a month. My functional medicine doctor reviewed the formula and said the multi-pathway approach is sound.
Each ingredient dosed at the level where published research showed results. Not underdosed to cut costs. Not overdosed to pad a label.
Six ingredients selected for what they do individually and how they work together.
A patented botanical extract clinically studied for HbA1c reduction and glucose metabolism support. Unlike commodity berberine with variable potency, Sugaheal is standardized and dosed at the level used in published clinical research. Sugaheal supports glucose metabolism through a separate metabolic pathway, without the GI issues associated with high-dose standalone berberine. Paired with a small 40mg supporting dose of Dihydro Berberine for complementary metabolic pathway coverage.
A more bioavailable form of berberine. At a small 40mg supporting dose, it complements Sugaheal through a separate metabolic pathway: avoiding the GI discomfort associated with high-dose standalone berberine.
A keystone gut bacterium that represents 1-5% of healthy gut flora. Clinically studied for its role in GLP-1 signaling, gut barrier integrity, and metabolic regulation. Akkermansia communicates directly with L-cells in the gut lining to support natural GLP-1 production.
Rich in inulin, a prebiotic fiber that specifically feeds Akkermansia muciniphila. Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut. Works with Beta Glucan as part of the prebiotic fuel system.
Standardized Grape Seed Extract (16% Monomers and 80% oligomeric proanthocyanidins / OPCs). Published research (PMC9834079) demonstrates that grape seed polyphenols promote Akkermansia growth in the gut microbiome, creating a synergistic effect with direct Akkermansia supplementation.
A soluble fiber with dual function: immune support and gut health. Beta Glucan supports healthy blood sugar levels by slowing glucose absorption and, alongside Chicory, helps feed Akkermansia and maintain a healthy gut environment. At 300mg, it provides effective fiber support without the digestive discomfort of higher doses.
Metabolic changes take time. If you don't notice improvements in 90 days, we'll refund you in full. No complicated forms, no judgment.
Subscribe and save. Every delivery ships free within the US. You save more and never have to think about reordering.
We want you to feel the results. If you're not happy, we'll give you a hassle-free, no-questions-asked refund processed immediately.
Independent lab verification for purity, potency, and accurate dosage
Screened for lead, mercury, arsenic, and cadmium below FDA thresholds
Manufactured in a GMP-compliant facility
Every ingredient and its exact dose printed on the label
GLP-1 (glucagon-like peptide-1) is a hormone your body produces naturally in the gut. It regulates blood sugar, appetite, and metabolic health. CLADETM supports natural GLP-1 production through three pathways: Sugaheal + Dihydro Berberine for glucose metabolism, Akkermansia for gut-based GLP-1 signaling, and prebiotics (Chicory + Beta Glucan) to maintain the environment where GLP-1-producing cells thrive.
Sugaheal is a patented, standardized botanical extract: not generic berberine powder. It's dosed at 410mg based on clinical research for HbA1c reduction, and supports glucose metabolism through a separate metabolic pathway without the GI issues associated with high-dose standalone berberine. CLADETM also includes 40mg of Dihydro Berberine (a more bioavailable form of berberine) as a small supporting dose to cover a complementary glucose metabolism pathway. Different mechanisms, both at disclosed doses.
Akkermansia muciniphila communicates with L-cells in your gut to support GLP-1 production, but it needs the right environment to colonize. Standardized Vinomerix Optima® (grape seed OPCs) promotes Akkermansia growth (PMC9834079). Chicory acts as a substrate for Akkermansia to establish and maintain populations in your gut, with Beta Glucan providing additional prebiotic support. Together: the bacteria, the fuel, and the growth promoter.
Most people report reduced cravings and digestive improvements within 2-3 weeks. Energy stabilization follows by weeks 3-4. Metabolic markers like fasting glucose often improve at 6-8 weeks. Our 90-day guarantee covers the full adaptation period.
CLADETM is a dietary supplement, not a medication. Many customers take it alongside metformin, but consult your healthcare provider first since both affect blood sugar. Your doctor can monitor levels and adjust medications as needed.
No. CLADETM is not a GLP-1 agonist drug and not a replacement for semaglutide or tirzepatide. Those drugs directly mimic GLP-1. CLADETM supports your body's natural GLP-1 production through nutritional and microbiome pathways. Consult your healthcare provider if you're considering or currently on GLP-1 medications.
Take 2 capsules daily with your largest meal. Taking with food supports absorption and aligns with the natural post-meal metabolic window. Consistency matters more than exact timing.
Side effects are uncommon. Some people notice mild digestive adjustment during the first week as the gut microbiome shifts. Taking with food usually prevents this. If needed, start with one capsule daily for the first week.
Yes. Plant-based capsules. Free from gluten, dairy, soy, and GMOs. No artificial additives, fillers, or magnesium stearate.
90-day satisfaction guarantee on quarterly plans. 30-day guarantee on monthly plans. If you're not satisfied for any reason, contact us for a full refund. No complicated forms, no restocking fees. We cover return shipping.
Transparent doses. Patented Sugaheal®. Multi-pathway metabolic support. Start with the quarterly plan for the strongest value and the full 90-day risk-free window.
The 90-Day GLP-1 Support Protocol is backed by a full 90-day risk-free guarantee. If you complete the protocol and your post-meal glucose curve, appetite signaling, or metabolic flexibility haven't shifted in ways you can feel, contact the team within 90 days for a full refund: no return required. The day-30 and day-60 milestones give you clear checkpoints so you know whether the protocol is working before the window closes.
You will receive an email notification before every charge. To pause or cancel, log into your customer account portal and manage your subscription in one click: no calls, no forms, no waiting period.
Log into your account portal and select "Skip next order." Your subscription resumes automatically on the following cycle. No charge is processed for the skipped month, and your pricing is preserved when you return.