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Stack Consolidation Guide

Stop Managing 4 Longevity Supplements.
Start the NAD+ and Polyphenol Protocol.

11 capsules across 4 brands. No CD38 protection in any of them. Sound familiar? There is a simpler way.

See the Consolidation Math
CLADE™ Longevity Complex bottle - NAD+ and polyphenol cellular protocol, 90 capsules
4.8 from 741 Reviews
6 Actives, 1 Protocol
90-Day Money-Back Guarantee
Free US Shipping

Your Morning Routine Looks Something Like This

You open the medicine cabinet and reach for the first bottle. NMN. Two capsules. Then the resveratrol. One capsule. An apigenin extract, two more. Magnesium, zinc, methyl folate, B12. By the time you are done, you have swallowed 11 capsules from 4 different brands before your first cup of coffee.

Four separate subscriptions. Four reorder dates you track in your head (or forget and end up doubling up on one while running out of another). Charges hitting your credit card on four different days.

And somewhere between the third and fourth bottle, a thought you have probably had more than once: there has to be a better way to do this.

You are not wrong. The problem is not the supplements themselves. NMN works. Resveratrol is well studied. Apigenin blocks the CD38 enzyme most people have never heard of. The problem is the way you are buying them: one mechanism at a time, from brands that each sell you one piece of the puzzle at premium prices.

NAD+ production without NAD+ protection. Polyphenol support scattered across a separate bottle. Eleven capsules every morning. And the nagging question of whether all those brands are even coordinating their doses.

"The day I stopped sorting through four supplement bottles before breakfast was the day this paid for itself."

Gregory M., Age 57, Verified Buyer

Before and After: The Stack Consolidation

Your Current Stack
4 different brands
11 capsules/day · $122/mo
CLADETM Protocol
1 bottle, 6 actives
3 capsules/day
$79/mo
Your Current Stack CLADE™ Protocol
Bottles on the shelf 4 different brands 1
Daily capsules 11 3
Monthly cost $122 at mid-market prices $79 ($65 on 90-day plan)
Active ingredients Scattered, uncoordinated doses 6 in 1 label
CD38 protection None Testosurge® 150 mg
Reorder dates to track 4-5 separate schedules 1 subscription
Label transparency Varies by brand Every dose printed

You see the numbers. Here is what actually replaces each bottle on your shelf.

See What Is Inside the Protocol

View the Full Protocol Breakdown

What Is Inside: 6 Actives, 2 Mechanisms, Zero Guesswork

Every ingredient in the CLADETM Longevity Complex maps directly to NAD+ support or polyphenol antioxidant support. No filler. No trendy additions. Six actives, each doing a specific job.

Replaces Standalone Resveratrol

Resveratrol 95 (300mg) + Vinomerix Optima® (210mg)

A polyphenol antioxidant pairing at a combined 510mg. Resveratrol 95 supplies the trans-resveratrol most people know from red wine research. Vinomerix Optima® adds a separate class of grape-derived OPCs. Two polyphenol sources instead of the one most standalone bottles give you.

The Gap in Your Current Stack

Testosurge® Apigenin-Rich (150 mg) - CD38 Protection

This is the gap in your current stack. An enzyme called CD38 increases with age and destroys your NAD+ before cells can use it. Testosurge® is a clinically studied apigenin extract that blocks CD38. Without it, the NMN you have been taking is fighting a losing battle. No mainstream competitor includes this.

Replaces Standalone NMN ($45/mo)

NMN (255 mg) + Trigonelline 50% (60 mg)

Two routes to NAD+ production instead of one. NMN is the direct precursor most people know. Trigonelline is converted to NAD+ through a distinct mechanism, the Preiss-Handler pathway, that is more efficient than the NMN salvage pathway. Trigonelline 50% enters the Preiss-Handler pathway and promotes NAD+ production via multiple enzymatic steps. Most standalone NMN brands have not caught up to this research yet.

Replaces Your Scattered Mineral Bottles ($32/mo)

Zinc + Magnesium + Methyl Folate + B12 (all 100% RDI)

These are not bonus ingredients. They are the cofactors the actives above need to function properly. Magnesium alone is required for mitochondrial ATP production. Most longevity protocols assume you are buying these separately. Now you do not have to.

Every dose is printed on the label. No proprietary blends. You can look up each amount and verify it against published research yourself.

"My naturopath confirmed my markers held steady after the switch. That was the data point I needed."

Lisa T., Age 49, Verified Buyer

The Replacement Math: Line by Line

What You Are Buying Now Monthly Cost What CLADE™ Replaces It With
Standalone resveratrol bottle $30/mo Resveratrol 95 300mg
Grape seed / OPC extract bottle $15/mo Vinomerix Optima® 210mg (510mg polyphenols combined)
Standalone NMN (various) $45/mo NMN 255 mg + Trigonelline 60 mg (salvage + Preiss-Handler)
Standalone apigenin bottle $0 (you did not have one) Testosurge® 150 mg (clinically studied CD38 blocker)
Magnesium + Zinc + Methyl Folate + B12 $32/mo All included at 100% RDI
TOTAL (4 bottles, mid-market pricing) $122/mo $79/mo for all 6 actives in 1 label

At mid-market prices those four bottles add up to about $122 a month. Buy the premium brands and it runs well past that. Against $79 that is $43 back every month, and you still have not counted the CD38 blocker most people never buy at all. What you also get is one label instead of four, with coordinated doses.

The 90-day plan drops the cost to $65 per month, which puts the saving at $57 a month.

You have seen the replacement math. Here is what the switch actually feels like.

Save $43/mo. One Label. Real CD38 Protection.

Start the Protocol at $65/mo

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What to Expect When You Make the Switch

The transition from a multi-bottle stack to one protocol is not just about convenience. When NAD+ support and polyphenol protection are active and coordinated in proper doses, users report a predictable pattern:

Weeks 1-2
The Morning Gets Simpler
Three capsules with breakfast. That is it. No sorting bottles, no checking which brand you are running low on. Users consistently report that the mental relief of a simplified routine is immediate. Energy stabilizes. Afternoon crashes smooth out as the NAD+ production and protection pathways work together from day one.
Weeks 3-4
You Start Noticing
Brain fog clears. Recovery from workouts and long days speeds up. These are downstream effects of dual-route NAD+ production and CD38 protection working in parallel. Howard R., 62, reported his post-gym soreness dropped from 3 days to 1.
Weeks 6-8
The Old Stack Bottles Gather Dust
This is when most users stop their individual supplements entirely. Gregory M., 57, went from 11 capsules across 4 brands to 3 from one. His bloodwork showed the same biomarker levels. Morning stiffness that had been a daily companion for years started resolving.
Month 3+
Compounding Returns
Deep cellular processes like NAD+ turnover and polyphenol antioxidant activity are cumulative. Three months of consistent NAD+ and polyphenol support produces compounding effects that a fragmented stack cannot match. This is why the 90-day plan exists: the biology rewards consistency.

"Week one was just the relief of a simpler morning. By week four, I realized I had not taken a single afternoon nap in two weeks. That had been my daily ritual for three years."

Howard R., Age 62, Verified Buyer

741 People Made the Switch. Here Are Four of Them.

"I tracked everything in a spreadsheet: reorder dates, doses, costs. Four brands, 11 capsules, a different charge hitting my card every week. Switched to CLADETM on the 90-day plan. My naturopath ran the same bloodwork panel at month two. NAD+ markers held steady. Inflammation markers actually improved. I cancelled four subscriptions in one afternoon. That felt better than the supplements themselves."
Gregory M., 57 - The Multi-Brand Manager
"I did not start taking longevity supplements because I wanted to. I started because my doctor found low NAD+ on bloodwork and suggested supplementation. Six months later I was juggling four separate products and dreading the daily pill routine. A friend mentioned CLADETM. I was skeptical about consolidation, but the simplicity alone was worth trying. Same markers, one bottle, $65 per month. I wish I had found this first."
Lisa T., 49 - The Reluctant Optimizer
"I play tennis three times a week and hike on weekends. Recovery was my biggest concern at 62. My old stack was NMN, magnesium, zinc, and a mitopure subscription. I was spending $210 per month and still missing the CD38 protection I did not even know I needed. CLADETM added polyphenol support and CD38 protection to my routine while cutting my pill count from 9 to 3. My post-match recovery dropped from three days to one. That is not a subtle difference."
Howard R., 62 - The Active Retiree
"I was the person who tried every new longevity supplement the podcasts recommended. NMN when Huberman talked about it. A resveratrol brand after one Sinclair episode. A CD38 blocker nobody else was talking about. My cabinet looked like a pharmacy. $340 per month at peak. CLADETM gave me a coordinated NMN and polyphenol protocol in three capsules and added the CD38 blocker I had never heard of. Dropping the guesswork alone paid for my gym membership."
Sandra M., 44 - The Early Adopter

You Do Not Have to Switch Cold Turkey

If dropping your entire stack overnight feels aggressive, do not. Here is the transition approach that works for most people:

Week 1-2

Start CLADETM Alongside Your Current Supplements

Yes, you will be doubling up temporarily. That is fine. This gives you a direct comparison baseline.

Week 3

Drop Your Standalone Minerals

Magnesium, zinc, methyl folate, B12. CLADETM covers these at 100% RDI.

Week 4

Drop Your NMN

CLADETM includes NMN plus Trigonelline (dual NAD+ pathway) plus CD38 protection you never had.

Week 5

Drop Your Standalone Resveratrol

CLADETM includes Resveratrol 95 (300mg) plus Vinomerix Optima® (210mg), 510mg of combined polyphenols.

Week 6

Drop Your Apigenin Bottle

If you have one. CLADETM includes Testosurge® apigenin-rich (150mg), the CD38 blocker most stacks never carry.

By week 6, you are down to one bottle. Track how you feel at each step. If anything feels off, the 90-day guarantee covers you completely. No restocking fees. No forms. Full refund.

Most people report they notice the simplicity improvement before they even finish the transition period.

You have seen the math, the testimonials, and the transition plan. Here is how to start with zero risk.

Start Alongside Your Current Stack. Risk Nothing.

Simplify Your Stack at $65/mo

Free US Shipping. 90-Day Guarantee. Cancel Anytime.

Questions About Making the Switch

Map it ingredient by ingredient. Resveratrol 95 plus Vinomerix Optima® replace your standalone polyphenol bottle. NMN plus Trigonelline replaces your standalone NMN with an additional NAD+ pathway. Testosurge® adds CD38 protection you never had. Foundation minerals replace your scattered mag/zinc/B-vitamin bottles. The only category CLADETM does not address is CoQ10, an intentional omission based on inconsistent longevity evidence in published research.
The CD38 enzyme destroys up to 90% of NAD+ before it reaches your cells. A 500mg dose without CD38 protection effectively delivers around 50mg of usable NAD+ precursor. CLADETM pairs 255 mg NMN with Testosurge® CD38 blocking, meaning more of that 255 mg actually converts to cellular NAD+. Production plus protection beats production alone. Multiple reviewers who switched from 500mg standalone NMN report the same or better results.
The 90-day plan includes a full money-back guarantee. No restocking fees, no forms, refund processed within 48 hours. Try it alongside your current stack for 30 days using the transition plan above. If you are not satisfied by the end of the guarantee period, send back the remaining supply for a full refund.
Yes. CLADETM targets NAD+ support and polyphenol antioxidant support specifically. CoQ10, fish oil, and other supplements that serve different functions (heart health, joint support, omega balance) can be taken alongside without overlap or interaction concerns. The consolidation is specifically for longevity supplements you are currently buying separately.
The Simplest Guarantee in Supplements
Start the 90-day plan at $65 per month. Run CLADETM alongside your current supplements for the first 30 days. Drop your individual products one by one using the transition plan. If at any point during the 90 days you feel like your old 4-bottle stack was delivering better results, send back the remaining supply. Full refund. No forms. No restocking fees. No questions.
  • 90-day money-back guarantee (quarterly plan)
  • 30-day money-back guarantee (monthly plan)
  • No restocking fees
  • Refund processed within 48 hours
  • Free US shipping on all subscriptions
CLADE™ Longevity Complex bottle with dramatic spotlight lighting

Save $43 a Month. Keep the Results.

Start the NAD+ and Polyphenol Protocol at $65/mo

Free US Shipping. 90-Day Guarantee. Cancel Anytime.

4.8 from 741 Verified Reviews 6 Actives in 1 Protocol Third-Party Tested GMP Certified

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult your healthcare provider before starting any supplement regimen.*